Contact

Office: CH2-322

Laboratory: CH2-314

Phone: +421 2 9014 9309

Education

2017                Full Professor of Medicinal Chemistry – Comenius University Bratislava, Slovakia

2009                Associate Professor – University of Veterinary and Pharmaceutical Sciences Brno, Faculty of Pharmacy, Czech Republic (Medicinal Chemistry)

2004                PharmDr., Ph.D. – Charles University, Faculty of Pharmacy, Czech Republic (Medicinal Chemistry)

2000                M.Sc. – Charles University Prague, Faculty of Pharmacy, Czech Republic (Pharmacy)

Professional Experience

2019–present Professor – Department of Analytical Chemistry, Faculty of Natural Sciences, Comenius University Bratislava, Slovakia

2019–present Professor – Institute of Neuroimmunology, Slovak Academy of Sciences, Slovakia (part-time job)

2019–present Professor – Regional Centre of Advanced Technologies and Materials/Department of Chemical Biology, Faculty of Science, Palacky University Olomouc, Czech Republic (part-time job)

2016–2019    Professor – Head of Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Comenius University Bratislava, Slovakia

2006–2019    Different positions: Asst. Prof., Assoc. Prof., Professor – Department of Chemical Drugs, Faculty of Pharmacy, University of Veterinary and Pharmaceutical Sciences Brno, Czech Republic

2004–2011    Different positions: Senior Specialist, Head of Laboratory, Senior Scientist – R&D Division, Zentiva Prague, Czech Republic

2000–2003    Scientist – Research Centre of Structure and Mechanism of Action of Potential Drugs, Faculty of Pharmacy, Charles University, Czech Republic & Zentiva Prague, Czech Republic

Research Activities

Pharmaceutical analysis and solid-state analytical techniques

Study of physicochemical properties of drugs, polymorphism, bioavailability, nanoparticles and ADME & DMPK

Design, synthesis and structure-activity relationships of anti-infectives and anti-invasive agents

Design, synthesis and structure-activity relationships of pesticides

Design, synthesis and structure-activity relationships of potential transdermal enhancers

 

Summary of Scientific & Publication Activity

Peer-reviewed publications: 237

Patents/Patent applications: 33

Peer-reviewed full-text conference contributions: 76

Conference abstracts: 263

University textbooks: 7

Monographs: co-author+co-editor 2; author/co-author of 40 chapters

Invited lectures: 73 (symposia, workshops), 30 (week-long sessions)

Sum of Times Cited without Self-Citations (Web of Science Core Collection): 2394 (I/2022)

h-Index (Web of Science Core Collection): 36 (I/2022)

 

More information:

Research Gate

Google Scholar

ORCID 0000-0003-2003-9052

Projects

Member of research group. HARTL, Jiří. “Biologically Active Derivatives of Pyrazine and Pyridine”. Grant Agency of the Charles University (GAUK 026/1998/B-CH/FaF) in 1998–2000.

Member of research group. KARLÍČEK, Rolf “Development, Preparation and Drug Technology”. Research Aims of the Ministry of Education of the Czech Republic (MSM 111600001) in 1999–2004.

Member of research group. KVASNIČKOVÁ, Eva. “Research Centre for Structure and Mechanism of Action of Potential Drugs”. Ministry of Education of the Czech Republic (LN00B125) in 2000–2004.

JAMPÍLEK, Josef. “Completion of Potential Antituberculotics and Antimycotics Series Synthesis”. University Development Foundation 2002 G4a – Students' Creative Activities – Natural Science Branches (FRVS 2245/G4/2002).

JAMPÍLEK, Josef. “Continuation of Potential Antituberculotics and Antimycotics Preparation”. University Development Foundation 2003 G6a – Students` Creative Activities – Natural Science Branches (FRVS 2998/G6/2003).

CHLUPÁČOVÁ, Marta and JAMPÍLEK, Josef. “Chalcones and Their Analogues as Potencial Drugs”. University Development Foundation 2003 G3a – Students' Creative Activities – Biomedicine Science Branches (FRVS 2970/G3/2003).

JAMPÍLEK, Josef. “Nanotechnology Approaches for Drug Delivery across Blood-Tissue Barriers”. Czech Science Foundation (GACR P304/11/2246) in 2011–2014.

KOS, Jiří and JAMPÍLEK, Josef. “Synthesis of Hydroxynaphthyl Carboxamides as Biologically Active Compounds.“ University of Veterinary and Pharmaceutical Sciences Brno (IGA VFU Brno 96/2012/FaF) in 2012.

Member of research group. DEVÍNSKÝ, Ferdinand. “Small Molecules in Biomedical Research”. Slovak Research and Development Agency (APVV-0516-12) in 2013–2017.

Member of research group. SEDMÍKOVÁ, Markéta and SALAŠOVÁ, Alena and VEČEREK, Vladimír. Centralized Development Project of the Ministry of Education of the Czech Republic 2014 “Improving Qualification of Students of Ph.D. Educational Programs & Postdoctorates of Agricultural and Veterinary Branches through Engagement in Multidisciplinary Interuniversity Teams”. Ministry of Education of the Czech Republic (MSMT Project No. C3) in 2014.

JAMPÍLEK, Josef. “Synthesis of Carboxamides of Kynurenic Acid as Biologically Active Compounds“.University of Veterinary and Pharmaceutical Sciences Brno (IGA VFU Brno, 37/2014/FaF) in 2014.

ZADRAŽILOVÁ, Iveta and JAMPÍLEK, Josef. “Study of Antimicrobial Properties of Newly Synthesized Prospective Chemotherapeutics“.University of Veterinary and Pharmaceutical Sciences Brno (IGA VFU Brno 52/2014/FaF) in 2014.

Member of research group. Sopuch, Tomáš. “Matrix Systems for Healing of Skin Defects for Human and Veterinary Use“. Technology Agency of the Czech Republic (TACR TA04010065) in 2014–2017.

ČERNÍKOVÁ, Aneta and JAMPÍLEK, Josef. “Evaluation of alaptide derivatives as potential modifiers of transdermal penetration“. University of Veterinary and Pharmaceutical Sciences Brno (IGA VFU Brno 302/2015/FaF) in 2015.

JAMPÍLEK, Josef. “Anti-Invasive Activity of Novel Antimicrobial Chemotherapeutics“. University of Veterinary and Pharmaceutical Sciences Brno (IGA VFU Brno 304/2015/FaF) in 2015.

Member of research group. SOBCZAK-KUPIEC, Agnieszka. “Innovative Composite Biomaterials Contained Bioactive Calcium Phosphates”. The National Centre for Research and Development, Warsaw, Poland (LIDER/037/481/L-5/13/NCBR) in 2015.

POSPÍŠILOVÁ, Šárka and JAMPÍLEK, Josef. “Investigation of Newly Synthesized Antibacterial Chemotherapeutics“. University of Veterinary and Pharmaceutical Sciences Brno (IGA VFU Brno 311/2016/FaF) in 2016.

Member of training group. Chemistry and Work (CHiP) – “Increasing the competences within the first and second cycle studies in the field of Chemistry and Chemical Technology” at the University of Silesia in Katowice, Poland. The project is co-financed by the European Union (Operational Program Knowledge Education Development, Priority Axis III Higher education for economy and development, Measure 3.1. Competences in higher education). Project No. DZP.381.47.2016.UGS in 2016-2017.

Member of training group. Chemistry and Fellowships (CIS) - implemented at the University of Silesia in Katowice, Poland, as part of the Operational Program Knowledge Education Development, co-financed by the European Union. Project No. DZP.381.053.2017.UGS in 2016-2017.

JAMPÍLEK, Josef. “Discovery of New Antimicrobial Chemotherapeutics“. Internal research grant of sanofi-aventis Pharma Slovakia, s.r.o. in 2017.

Member of training group. Chemistry and Work (CHiP) – “Increasing the competences within the first and second cycle studies in the field of Chemistry and Chemical Technology” at the University of Silesia in Katowice, Poland. The project is co-financed by the European Union (Operational Program Knowledge Education Development, Priority Axis III Higher education for economy and development, Measure 3.1. Competences in higher education), Project No. DZP.381.064.2018.UGS.UGS in 2017-2018.

JAMPÍLEK, Josef. “Design of New Hydroxy(aza)naphthalenes“. Internal research grant of sanofi-aventis Pharma Slovakia, s.r.o. in 2018.

DEVÍNSKÝ, Ferdinand and JAMPÍLEK, Josef. “Design of new small molecules and bioactive nanoparticules for the therapy of inflammatory and degenerative diseases of bones and knuckles”. Slovak Research and Development Agency (APVV-17-0373) in 2018–2022.

Member of research group. MASÁR, Marián. “Application possibilities of new orthogonal miniaturized and microseparation analytical systems for fast monitoring of biological, environmental and forensic samples”. Slovak Research and Development Agency (APVV-17-0318) in 2018–2022.

Member of research group. MASÁR, Marián. “Development of new techniques for treatment of biomedical and environmental samples for combined advanced analytical methods”. Minister of Education, Science, Research and Sports of the Slovak Republic & the Slovak Academy of Sciences (VEGA 1/0787/18) in 2018–2020.

Member of training group. “Integrated Development Program of the University of Silesia in Katowice” (project number DZP.381.016.2019.UGS). The project is co-financed by the European Union under the European Social Fund, Operational Program Knowledge Education Development, Priority axis: III. Higher education for economy and development. Measure: 3.5 Comprehensive programs of higher education institutions, number of co-financing agreement POWR.03.05.00-00-Z117/17-00 in 2019-2020.

Member of research group. TRÁVNÍČEK, Zdeněk. “Small molecules with application potential in field of medical and material research”. Palacký University in Olomouc (IGA_PrF_2020_023) in 2020–2021.

Professional Stays Abroad

2009–present Institute of Chemistry, University of Silesia in Katowice, Poland (visiting professor)

2016–present School of Chinese Medicine, Hong Kong Baptist University, Hong Kong SAR, China (visiting professor)

 

2021                Department of Physical Chemistry and Biophysics, Pharmaceutical Faculty, Wroclaw Medical University, Poland (invited professor)

2019                Faculty of Health Sciences, University of Macau, Macau SAR, China (invited professor)

2018                Department of Pharmaceutical Sciences, College of Pharmacy, Midwestern University, Phoenix, AZ, USA (invited professor)

2018                U.S. Food and Drug Administration, Silver Spring, MD, USA (invited expert)

2017                Bosch Institute, Faculty of Medicine and Health, University of Sydney, NSW, Australia (invited professor)

2017                Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Ljubljana, Slovenia (invited professor)

2016                School of Pharmaceutical Sciences, Guizhou Medical University, Guiyang, China (invited professor)

2016                Key Laboratory of Chemistry for Natural Products of Chinese Academy of Sciences, Guiyang, China (invited professor)

2016                Department of Organic Chemistry, Institute of Chemical Technology and Engineering, Poznan University of Technology, Poland (invited professor)

2016                Institute of Medicinal Chemistry, University of Veterinary Medicine and Pharmacy in Košice, Slovakia (invited professor)

2015                Institute of Inorganic Chemistry and Technology, Faculty of Chemical Engineering and Technology, Cracow University of Technology, Poland (invited professor)

2014                Department of Pharmaceutical and Toxicological Chemistry, Faculty of Pharmacy, South Kazakhstan State Pharmaceutical Academy, Shymkent, Kazakhstan (visiting professor)

2014, 2015     Department of Biochemistry and Neurobiology, Faculty of Material Science, AGH University of Science and Technology, Krakow, Poland (invited professor)

2014                Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Kazakh National Medical University, Almaty, Kazakhstan (visiting professor)

2000                Medicinal Chemistry Institute, Heidelberg University, Germany (research fellowship)

Other activities

Supervisor of defended 20 Diploma students (M.Sc.) and 15 Rigorous students (PharmDr./RNDr.) and 7 Ph.D. students

External lecturer – Institute of Postgraduate Medical Education Prague, Czech Republic (since 2009)

 

Member of Editorial Boards:

ADMET & DMPK

ChemistrySelect

Current Chinese Chemistry

Current Drug Discovery Technologies

Foundations (Editor-in-Chief of 'Medical Sciences' Section)

Frontiers in Bioscience-Landmark (Editor-in-Chief of 'Pharmacology & Toxicology' Section)

Medicinal Chemistry

Military Medical Science Letters

Molecules

Nanomaterials

 

Guest Editor:

ADMET & DMPK

BioMed Research International

Current Medicinal Chemistry

Current Organic Chemistry

Current Pharmaceutical Design

International Journal of Molecular Sciences

Molecules

Monatshefte für Chemie

Nanomaterials

Symmetry

 

Member:

Czech Chemical Society

International Association of Physical Chemists

Slovak Chemical Society

Working Group on New TB Drugs